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  • Lysodren® is used to treat Cushing's disease.

Lysodren® Tablets


*Prescription Required: Vetsource®, our pharmacy provider, may need to contact your veterinary hospital for prescription verification.

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We'll collect your pet information to verify this prescription with your veterinarian before shipping. Your prescription order will ship upon veterinarian approval.
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Product Information

Lysodren® tablets are used to treat Cushing's disease (hyperadrenocorticism) by suppressing adrenal gland function. This condition generally requires a lifetime of treatment.

Active Ingredients


Side Effects
Side effects may include decreased appetite, vomiting and diarrhea, lethargy, or weakness.
Other side effects may occur. If you notice anything unusual, contact your veterinarian

Developed For


Product Benefits

Lysodren® is used to treat Cushing's disease.

Usage Guidelines

Lysodren® should be given orally as directed by your veterinarian.

This medication does not have an FDA approved indication for use in animals, but it is a common and acceptable practice for veterinarians to prescribe this human medication for use in animals.
Pregnant women or women trying to get pregnant should not handle this medication. The safety of Lysodren® in pregnant, nursing, or breeding dogs has not been determined.

Make sure to tell your veterinarian what other medication you are giving to your pet. Quite often your veterinarian may prescribe two different medications, and a drug interaction may be anticipated. In this case, your veterinarian may vary the dose and/or monitor your pet more closely. The following drugs can potentially interact with mitotane: spironolactone, barbiturates, warfarin, insulin, and CNS depressants. Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.

Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies. If your pet displays symptoms of an allergic reaction, call your veterinarian immediately or go to a veterinary emergency clinic. Symptoms may include but are not limited to: swollen lips, tongue, face, airways; difficulty breathing; agitation; profuse salivation; vomiting; widespread hives and itching.