By Rania Gollakner, BS DVM, MPH

What is robenacoxib?

Robenacoxib (brand name: Onsior®) is a coxib-type nonsteroidal anti-inflammatory drug (NSAID) used to treat inflammation and pain in dogs and cats. This drug is often used before and after surgical procedures because robenacoxib targets inflamed tissues.

How do I give my pet robenacoxib?blister_pack_medication

Robenacoxib is available both as an injection and oral tablets. The injection is administered by your veterinarian at the hospital, and the tablets are given at home by mouth, with or without food. The tablets should be given whole and are not designed to be broken.

This medication will take effect quickly, in about 1 to 2 hours, and improvement in clinical signs should follow.

Are there any potential side effects from robenacoxib?

While most pets do well with robenacoxib, pets that are hypersensitive to it or other NSAIDs could have side effects including anorexia (lack of appetite), lethargy, depression, vomiting, diarrhea, kidney disease, and kidney failure. Bleeding or infection at the incision site is also possible.

This moderate-acting medication should stop working in a few days, although effects can be longer in pets with liver or kidney disease.

Are there any risk factors for this medication?

Robenacoxib should not be used in patients that are dehydrated, on diuretic therapy, or have existing renal, heart, or liver disease. Blood work should be performed prior to starting this medication to check for these risk factors.


Are there any drug interactions I should be aware of?

Robenacoxib should not be administered with any other NSAIDs or corticosteroids. Tell your veterinarian about any medications or supplements you are giving to your pet.


Is there any monitoring that needs to be done with this medication?

Pets should be monitored closely for clinical signs/side effects that may show a hypersensitivity. If any of these signs are noticed, especially a decreased appetite or lethargy, stop administering the medication and call your veterinarian.


What should I do in case of emergency?

If you suspect a negative reaction to the medication, call your veterinarian immediately. If your veterinarian is not available, follow the directions for contacting an emergency facility.

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