Hydrocortisone Ophthalmic

By Kayla Hyland, DVM

What is hydrocortisone ophthalmic?

Hydrocortisone ophthalmic is a topical steroid medication used to treat surface inflammation in the conjunctiva of the eye, usually in combination with other eye medications. It is used to treat inflammatory eye conditions in cats and dogs. Hydrocortisone ophthalmic is not commercially available as a sole agent; it is available in a combination product with antimicrobials.

Depending on the combination of medications, its use may be considered “off label” or “extra label”. Its use to treat conditions other than inflammation of the eye or conjunctiva would also be considered off label. Many drugs are commonly prescribed for off-label use in veterinary medicine. In these instances, follow your veterinarian’s directions and cautions very carefully.

How do I give my pet hydrocortisone ophthalmic?

Hydrocortisone ophthalmic comes in ointment or liquid drop form (alone or in combination with an antimicrobial).

  • Ointments and drops are given topically directly into the eye. 
  • Wash your hands before giving your pet this medication.
  • Do not allow the dropper tip to touch your animal’s eye or any other surface to prevent contamination.
  • If you are administering more than one eye medication to your pet, wait 5 to 10 minutes between each medication. Give eye drops before eye ointments.
  • Give this medication to your pet for the entire time prescribed by your veterinarian, even if it appears that your pet is feeling better.

What if I miss giving my pet the medication?

Give the missed dose as soon as you remember and then continue with the regular dosing schedule. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not give the pet two doses at once.

Are there any potential side effects from hydrocortisone ophthalmic?

Hydrocortisone ophthalmic may cause the following side effects:

  • irritation, stinging, or swelling
  • drooping of the eyelid

The following reactions are rare; if they occur, contact your veterinarian immediately:

  • an allergic reaction such as irregular breathing, rash, fever, puffiness and swelling around the face

Drug sensitivities can develop over time with repeated exposure. Your pet may have no reaction after the first few doses, but may develop a sensitivity later. It is important to watch for signs of an allergic reaction over the entire course of treatment.

Other side effects may occur. If you notice anything unusual, contact your veterinarian immediately. This moderate-acting medication should stop working within a few days.

Are there any risk factors for this medication?

This medication should be AVOIDED in:

  • birds
  • animals with suspected viral or fungal infections
  • animals with corneal ulceration
  • animals that are allergic to any component

This medication should be used with CAUTION in animals who:

  • have diabetes
  • have glaucoma
  • are pregnant or nursing

Are there any drug interactions I should be aware of?

No known drug interactions have been reported for this medication. Be sure to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your pet is taking before starting any new treatment.

Is any monitoring needed with this medication?

Your veterinarian may schedule a follow-up visit after the course of medication is complete to ensure the condition has been cleared and/or do additional testing to ensure this is the right medication for the type of condition that is present. In this case, follow your veterinarian’s directions.

How do I store hydrocortisone ophthalmic?

  • Store the medication in its original container, protected from light, at room temperature. 
  • Follow storage and expiration recommendations for specially compounded medications.
  • Keep medication out of reach of children and pets.

What should I do in case of emergency?

If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately. If they are not available, follow their directions in contacting an emergency facility.

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