Dr. Little received a Bachelor of Arts from University of Pennsylvania in 1990 and returned to University of Pennsylvania Veterinary School to graduate Summa cum Laude with Veterinary Medical Degree in 1996. She completed a one year rotating internship at Rowley Memorial Animal Hospital in Springfield Massachusetts in 1997. After one year of general practice in Virginia, she matched for a surgery residency at Iowa State University in 1998. Upon completion of the three year surgery residency, she moved to Southern California for her first surgery position and achieved surgery board certification in 2002.

She has practiced in Southern California and Phoenix, Arizona, and ultimately settled in South Pasadena at CM Surgical Specialty group in 2008. She has been a co-owner of CM Surgical Specialty Group until selling the practice to VCA in 2018. She continues to practice orthopedic and select soft tissue surgeries at VCA TLC Pasadena Veterinary Specialty and Emergency. Dr. Little has been published in the Five-Minute Veterinary Consultation textbook.

Dr. Little also has a strong interest in physical rehabilitation therapy for animals and has achieved certification as a canine rehabilitation therapist through the Canine Rehabilitation Institute. Dr. Little divides her time between surgery and rehabilitation therapy.

In her down time, Dr. Little spends time with her family and ever changing number of cats and enjoying all the activities of Southern California.