What is nystatin combination?
Nystatin combination (brand names Panalog®, Cortalone®, Animax®, Derma-vet®, Quadritop®, Dermalog®, Dermalone®, EnteDerm®, Resortin®) is a topical anti-yeast medication in combination with other medications, such as steroids or antibiotics, and it is used to treat skin lesions in cats, dogs, and other mammals.
Depending on the product and how it is used, its use in cats, dogs, or other mammals to treat inflammatory skin conditions may be off label (extra label). Many drugs are commonly prescribed for off-label use in veterinary medicine. “Off label” means the drug is being used in a way that has not been reviewed or approved by the U.S. Food and Drug Administration (FDA) or Health Canada. In these instances, follow your veterinarian’s directions and cautions carefully, as they may be significantly different from those on the label.
How is nystatin combination given?
- Nystatin combination is applied topically to the skin on the affected area.
- If necessary, trim the hair to allow the medication to reach the lesion.
- Do not allow your pet to lick or chew the treated area for at least 30 minutes after application.
- Wear gloves when applying this medication and wash hands after application.;
- Avoid contact with eyes, nose, or mouth.
This medication should take effect within 1 to 2 hours. Effects may not be obvious, but gradual improvements are usually noticeable after a few days.
What if I miss giving my pet the medication?
If you miss a dose, give it when you remember, but if it is close to the time for the next dose, skip the dose you missed and give it at the next scheduled time, and return to the regular dosing schedule. Never give your pet two doses at once or give extra doses.
Are there any potential side effects?
Nystatin may cause the following side effects:
- localized skin inflammation
Serious side effects may occur. If any of the following signs develop, stop giving Nystatin and contact your veterinarian immediately:
- loss of appetite
- vomiting
- diarrhea
- sudden hearing loss
- worsening ear pain
- head tilt, mouth sores
- worsening lesions
- increased thirst
- more frequent urination
- skin thinning
- worsening hair loss
- new infections at the application site
This moderate-acting medication should stop working in a few days, although effects can be longer in pets with liver or kidney disease. Drug sensitivities can develop over time, with repeated exposure. Your pet may have no reaction after the first few doses but may develop a sensitivity later. It is important to watch for signs of an allergic reaction over the entire course of treatment. Other side effects may occur. If you notice anything unusual, contact your veterinarian immediately.
Are there any risk factors for this medication?
Nystatin combination should NOT BE USED on pets that:
- are allergic to it
- have tuberculosis infections of the skin
- have a ruptured ear drum
Nystatin combinations that include corticosteroids should NOT BE USED on pets that are pregnant.
Nystatin should be USED WITH CAUTION in pets that:
- require a large treatment area
- are smaller in size
- have recurring ear infections
Are there any drug interactions I should be aware of?
There are no specific drug to drug interactions with nystatin combinations. Be sure to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your pet is taking.
This medication, when combined with a corticosteroid, may interact with allergy testing; discontinue its use 2 weeks prior to allergy testing.
Is any monitoring needed with this medication?
- No specific monitoring is required while your pet is taking this medication.
- Your veterinarian may monitor your pet to be sure that the medication is working. Monitor your pet at home for serious side effects.
How do I store nystatin combination?
- Store in the original container at room temperature, below 86°F (30°C).
- Store away from light.
What should I do in case of emergency?
If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately. If they are not available, follow their directions in contacting an emergency facility.
