Terbinafine Topical

By Lauren R. Forsythe, PharmD, MBA, DICVP; Rania Gollakner, BS, DVM, MPH

What is terbinafine?

Terbinafine (brand name Lamisil®) is a topical antifungal used occasionally to treat fungal skin infections in dogs. It is not as effective for treating fungal skin infections in cats.

Terbinafine is also found as an ear solution in combination with other medications for use in dogs (e.g., Claro®).

Its use as a topical antifungal in dogs is “off label” or “extra label”. Many drugs are commonly prescribed for off-label use in veterinary medicine. In these instances, follow your veterinarian’s directions and cautions carefully, as they may be significantly different from those on the label.

How do I give my pet terbinafine?

  • Terbinafine is used topically, on the skin, as a cream or spray, or as an ear solution in combination with other medications. 
  • Take care to avoid your pet’s eyes and mucous membranes.
  • Wear gloves while applying this medication or wash hands immediately after application. 

This medication can take a few weeks before full effects are noted, but gradual improvements are usually noticeable after a few days.

What if I miss giving my pet the medication or my shipment is late?

If you miss a dose, give it as soon as you remember, and then continue with the regular dosing schedule. However, if it is almost time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not give the pet two doses at once.

Are there any potential side effects?

Skin irritation is possible but unlikely to occur.

This short-acting medication should stop working within 24 hours, although effects can be longer in pets with liver or kidney disease.

Are there any risk factors for this medication?

No risk factors have been noted, but topical terbinafine has not been studied extensively in animals.

Are there any drug interactions I should be aware of?

No interactions have been noted. However, be sure to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your pet is taking before starting any new treatment.

Is any monitoring needed with this medication?

No specific monitoring is needed while your pet is taking this medication. Your veterinarian may monitor your pet to be sure that the medication is working.

How do I store terbinafine?

  • Store cream or spray at room temperature (25°C or 77°F).
  • Store in a tightly sealed container, away from light.

What should I do in case of emergency?

If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately. If they are not available, follow their directions in contacting an emergency facility.

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