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Kai Shiu

Dr. Kai Shui
Veterinary Specialist
Availability: Monday
Dr. Kai Shui

At a Glance

Practicing Since:


Board Certified:

Medical Oncology

Specialties Include:

Goal oriented diagnostic planning
Head and neck tumors
Clinical trials

My Pets:

Joey Tribbiani - The “means well but not so smart” kitty

Professional Affiliations:
American College of Veterinary Internal Medicine (Oncology) Diplomate, 2010
WVMA Professional Education Committee
Veterinary Cancer Society
American Veterinary Medical Association
Wisconsin Veterinary Medical Association
Royal College of Veterinary Surgeons
American College of Veterinary Internal Medicine
Dane County Veterinary Medical Association

Board Certification:
American College of Veterinary Internal Medicine (Oncology) Diplomate, 2010

BSc (Hons) In Veterinary Pathology, Royal Veterinary College, 2004
BVMS (DVM equivalent), University of Glasgow, Scotland, 2006

Rotating small animal medicine and surgery internship from 2006-2007 at Cornell University Hospital

Medical Oncology, University of Wisconsin, Madison, 2010

Dr. Shiu has been trusted with the care of dogs and cats with cancer in SW Wisconsin since 2007, and is known for his practical yet compassionate approach to his clients and patients. His philosophy is to provide as much support as he can to owners going through the difficulty process of managing their loved one's cancer. He strongly believes in providing options with the owner's goals, budget and patient's prognosis in mind – there is no such thing as a “right” or “wrong” decision. As an advocate for individualized therapy, he is able to work with a client to develop unique, but evidence based protocols that suit the client and patient's needs. 

Dr. Shiu has published and presented nationally research in both canine and feline oncology and he continues to contribute to research studies and publications. He brought the first electrochemotherapy service to the Midwest in 2017, with patients travelling from all over the midwest to receive this new cancer treatment. Active in the local veterinary community, he founded the Dane County Veterinary Medical Association, and fundraised over $500,000 for cancer research in the past five years. He was founding chair of the national scientific advisory board for a national comparative oncology research foundation for 3 years, before co-founding a local foundation called Czar’s Promise which funds UW American Family Children’s Hospital as well as local veterinary cancer research and treatment. 

After veterinary school in Glasgow, Scotland, Dr. Shiu completed a rotating small animal medicine and surgery internship from 2006-2007 at Cornell University Hospital for Animals, where he developed his love for oncology, and more specifically, the special bond between oncology patients and their owners. He then moved to Madison to pursue a three year residency in Medical Oncology at UW Madison. Following completion of his residency, he started the first private practice oncology service in SW Wisconsin, here at VESVSC in 2010.   

The highest compliment Dr Shiu feels he receives is when the veterinarians not only trust him with their patients, but with the care of their own pets facing a diagnosis of cancer.  


"Dr. Shiu is not only a fellow veterinary colleague, Oncology specialist I often refer my own clients for consult, and an active community member in the successful PuppyUp fundraiser; but he has personally provided Oncology guidance and therapy for my own young poodle with Digital melanoma and my father's seeing eye service dog suffering from hemangiosarcoma. He is a dedicated, knowledgeable, caring, forthright, and personable veterinarian who really goes the distance for each and every one of his patients and their humans. Dr. Shiu and the team at VES is only a phone call away and I feel very comforted knowing my own pets and those of my clients are in the best hands." - Dr. Laura Oxley

Papers Authored
Immunoglobulin G4-Related Disease in a Dog
Abstract: Immunoglobulin G4‐related disease (IgG4‐RD), which affects many organ systems, has been recognized as a distinct clinical entity in human medicine for just over a decade but has not been previously identified in dogs. In humans, IgG4‐RD is characterized by diffuse IgG4‐positive lymphoplasmacytic infiltrates that commonly lead to increased serum concentrations of IgG4 and IgE, peripheral eosinophilia, tumorous swellings that often include the parotid salivary glands, obliterative phlebitis, and extensive fibrosis. Herein we describe the diagnosis, clinical progression, and successful treatment of IgG4‐RD in an 8‐year‐old female spayed Husky mixed breed dog. Immunoglobulin G4‐related disease should be considered as a differential diagnosis for dogs with vague clinical signs, lymphoplasmacytic swellings, restricted polyclonal gammopathy, eosinophilia or some combination of these findings.
Authored: Colopy, L, Shiu, KB ;Snyder,L ; Avery,A ; Rout, E; Moore, R
Published: Journal of Veterinary Internal Medicine 2019
Post-Surgical Outcome and Prognostic Factors in Canine Malignant Melanomas of the Haired Skin: 87 Cases (2003-2015)
Abstract: The medical records of 87 dogs treated with surgery for cutaneous malignant melanoma (CMM) of the haired skin were retrospectively reviewed for overall survival time (OST), progression-free survival time (PFS), and prognostic factors. The post-surgery median PFS and median OST were 1282 days and 1363 days, respectively. The post-surgery metastatic rate was 21.8% with a local recurrence rate of 8%. Increasing mitotic index (MI) was predictive of a significantly decreased OST and PFS on multivariable analysis [hazard ratio (HR): 1.05, 95% confidence interval (CI): 1.02 to 1.07 and HR: 1.04, 95% CI: 1.02 to 1.06, respectively]. Increasing age was likewise predictive of a significantly decreased OST and PFS on multivariable analysis (HR: 1.39, 95% CI: 1.17 to 1.65 and HR: 1.33, 95% CI: 1.14 to 1.54, respectively). These results confirm clinical impressions that long survival times are likely in dogs diagnosed with malignant melanoma of the haired skin when treated with surgery alone.
Authored: Laver T, Feldhaeusser BR, Robat CS, Baez JL, Cronin KL, Buracco P, Annoni M, Regan RC, McMillan SK, Curran KM, Selmic LE, Shiu KB, Clark K, Fagan E, Thamm DH
Published: Canadian Veterinary Journal 2018
Retrospective Evaluation of Toceranib Phosphate (Palladia) Use in Cats With Mast Cell Neoplasia
Objective: The purpose of this study was to solicit and compile data from practicing veterinary specialists regarding their use of toceranib in cats with mast cell neoplasia and to provide initial assessment of possible clinical benefit and adverse events. 
Authored: Berger EP, Johannes CM, Post GS, Rothchild G, Shiu KB, Wetzel S, Fox LE
Published: J Feline Medicine & Surgery 2018
What Is Your Diagnosis? Granules Galore!
Authored: Sample S, Webb JL, Behr M, Shiu KB
Published: Veterinary Clinical Pathology 2015
Intravenous Administration of Docetaxel to Cats With Cancer
Objective: Document adverse effects of i.v. administration of docetaxel to cats.
Authored: Shiu KB, McCartan L, Kubicek L and Vail DM
Published: Journal of Veterinary Internal Medicine 2011
Predictors of Outcome in Dogs With Subcutaneous or Intramuscular Hemangiosarcoma
Objective: To identify prognostic factors in a large group of dogs with subcutaneous or intramuscular hemangiosarcoma (HSA) or both. Design-Multi-institutional retrospective cohort study. Animals-71 dogs with subcutaneous or intramuscular HSA.
Authored: Shiu KB, Flory AB, Anderson CL, Wypij J, Saba C, Wilson W, Kurzman I, Chun R
Published: Journal of the American Veterinary Medical Association 2011
See our departments


Cancer is the leading cause of death in dogs and cats. Advances in our understanding of cancer biology have helped pets live longer, with an excellent, dignified quality of life. Our goal is to give you all the information you need to make the right decision for you and your pet. We may offer additional diagnostics such as aspirates, biopsies or staging to refine a treatment plan that may include chemotherapy, surgery or radiotherapy; all with the goal if improving your pet's quality of life. At Veterinary Specialty Center, you'll have the peace of mind knowing you will see the same board certified oncologist at every visit.

We perform advanced diagnostic procedures; including ultrasound and biopsy procedures; or interpret tests already performed by your veterinarian to identify the type, location, and behavior of a tumor. After collecting this information and consulting with your veterinarian, our cancer specialist will describe the behavior and stage of the cancer, as well as the likely outcomes and treatment options to the pet owner. These options are tailored to the animal's particular cancer, prognosis and lifestyle and will be consistent with the owner's goals for the pet. Cancer treatments that may be recommended can include medical treatments (vaccines, chemotherapy, anti-vascular drugs), surgery and/or radiotherapy.

Some types of cancer are very responsive to chemotherapy. The approach for using chemotherapy in dogs and cats is very different from that in humans; our lower doses of chemotherapy often result in quick improvement in quality of life during treatment, rather than the approach in human oncology of using much larger doses of chemotherapy resulting in severe side effects but higher cure rates. Many chemotherapy protocols can often be covered by pet insurance.

Why See An Oncologist?

When owners are faced with cancer in their pets, veterinarians will recommend or offer a consultation with a veterinary oncologist. An Assessment of the pet's history and physical examination is then done by an oncologist and will sometimes recommend a staging and treatment regimen. This regimen can be performed locally with their own veterinarian or at a specialist center depending on the pet’s treatment plan.

Our Oncology Team

VCA Veterinary Emergency Service & Veterinary Specialty Center

4902 East Broadway

Madison, WI 53716

Main: 608-222-2455

Fax: 608-467-6014

Hospital Hours:

    Mon-Sun: Open 24 hours

Specialty Services Hours:

Mon-Fri: 8:00 am - 5:00 pm

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