Gentamicin - Ophthalmic

By Rania Gollakner, BS, DVM

Medications

What is gentamicin?

Gentamicin (brand names: Genoptic®, Gentak®) is a topical aminoglycoside antibiotic used to treat certain bacterial infections. It can also be used to treat end-stage glaucoma (increased eye pressures).

Its use in cats and dogs to treat bacterial infections in the eye and glaucoma is sometimes 'off label' or 'extra label'. Many drugs are commonly prescribed for off label use in veterinary medicine. In these instances, follow your veterinarian’s directions and cautions very carefully as their directions may be significantly different from those on the label.

How is gentamicin given?

Gentamicin can be found in many forms, but for the eye it is given as an ointment or liquid solution. These medications are applied directly to the eye to treat infections. Do not touch the tip of the bottle or tube to the eye or any other surface. Do not apply this medication within 5 minutes of administering another medication in the eye. Keep the cap tightly closed when not using the medication. This medication will take effect quickly, in about 1 to 2 hours, but outwardly effects may take a few days to be recognized.

For the treatment of glaucoma, your veterinarian will administer the medication during a surgical procedure in hospital.

What if I miss giving my pet the medication?

If you miss a dose, give it when you remember, but if it is close to the time for the next dose, skip the dose you missed and give it at the next scheduled time, and return to the regular dosing schedule. Never give your pet two doses at once or give extra doses.

Are there any potential side effects?

Side effects of this medication include eye irritation and burning, and redness or mild swelling of the tissue around the eye. If this occurs, discontinue the medication and contact your veterinarian. Rarely, allergic reactions and thrombocytopenic purpura (bruising and bleeding) can occur. This short-acting medication should stop working within 24 hours.

Are there any risk factors for this medication?

Gentamicin should not be used in patients with a history of hypersensitivity or allergy to it, or in pets that have a full-thickness wound in the eye.

Are there any drug interactions I should be aware of?

Drug interactions have not been noted at this time with topical use of gentamicin.

Be sure to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your pet is taking.

Is there any monitoring that needs to be done with this medication?

There is no specific monitoring that needs to be done while your pet is taking this medication. Your veterinarian may monitor your pet to be sure that the medication is working. Your pet should be rechecked before treatment is discontinued.

How do I store gentamicin?

Gentamicin should be stored in the refrigerator or at controlled room temperature, protected from moisture, sunlight, and freezing.

Do not use if the color changes, it becomes cloudy, or if particles (grit) are seen in the solution.

What should I do in case of emergency?

If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately. If they are not available, follow their directions in contacting an emergency facility.

Free First Exam

Our pet care experts can't wait to welcome you. 

Find a Local VCA

We're here for you and your pet in 43 states. 
Loading... Please wait