What is moxidectin + fluralaner topical?
Moxidectin + fluralaner topical (Bravecto® Plus, Vitrecto®) is used in cats to prevent heartworms, to treat and prevent fleas, and to treat intestinal parasites (hookworms and roundworms). It also kills black-legged ticks (deer ticks).
It is used off label (extra label) in cats to treat other types of ticks, as well as skin mites and ear mites. Many drugs are commonly prescribed for off-label use in veterinary medicine. “Off label” means the drug is being used in a way that has not been reviewed or approved by the U.S. Food and Drug Administration (FDA) or Health Canada. In these instances, follow your veterinarian’s directions and cautions carefully, as they may be significantly different from those on the label.
How is moxidectin + fluralaner given?
- Moxidectin + fluralaner topical is applied topically to the skin at the base of the neck.
- When applying, part the cat’s hair to ensure that the medication is placed on the skin and not into the hair.
- For the first 30 minutes after application, monitor to ensure your pet does not lick the product.
- Do not apply this medication to irritated skin.
- Do not bathe your pet for at least 4 days after application.
- Do not touch the medicated area until the product is no longer noticeable.
This medication starts killing fleas within 12 hours of application and ticks within 48 to 72 hours of application.
What if I miss giving my pet the scheduled dose?
If you miss a dose, give it as soon as you remember and start a new every-two-month dosing schedule. For example, if you forgot to give your pet their dose on June 1 and remember on June 18, give the dose on June 18 and start a new schedule. You will give your pet the next dose on August 18. Do not give your pet two doses at once. Contact your veterinarian if you are concerned about a missed dose.
Are there any potential side effects?
Moxidectin + fluralaner topical may cause the following side effects:
- Vomiting
- Hair loss at the application site
- Itching
- Diarrhea
- Lethargy
- Excessive drooling
- Dry skin
If your pet ingests moxidectin + fluralaner topical, side effects may include:
- Salivation
- Vomiting
Fluralaner belongs to a class of drugs called isoxazolines, which have been associated with neurological side effects. If any of the following signs develop, stop giving moxidectin + fluralaner and contact your veterinarian immediately:
- Tremors
- Seizures
Drug sensitivities can develop over time, with repeated exposure. Your pet may have no reaction after the first few doses but may develop a sensitivity later. It is important to watch for signs of an allergic reaction over the entire course of treatment and notify your veterinarian if you have any concerns.
Other side effects may occur. If you notice anything unusual, contact your veterinarian immediately. This long-acting medication is designed to work for at least 8 weeks. However, negative side effects are usually short-lived if they occur at all.
Are there any risk factors for this medication?
DO NOT USE moxidectin + fluralaner in:
- Cats that are hypersensitive or allergic to it
- Cats that are sick, debilitated, or underweight
USE WITH CAUTION in:
- Cats with low body fat (sick or very young), as they are more prone to side effects
- Cats with known neurological disorders
- Cats that are breeding, pregnant, or nursing (safety has not been established)
Are there any drug interactions I should be aware of?
Certain medications should be used with caution when given with moxidectin + fluralaner topical, including:
- Benzodiazepines
Be sure to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your pet is taking before starting any new treatment.
Is any monitoring needed with this medication?
- Your veterinarian will let you know when and how they want to reassess your pet to ensure the medication is working and not causing side effects.
- At home, monitor for any side effects such as those noted above. If any occur, stop using the medication and contact your veterinarian.
How do I store moxidectin + fluralaner topical?
- Store this medication in its unopened pouch between 39°F and 77°F (4°C and 25°C).
- Keep the container out of reach of children and pets.
What should I do in case of an emergency?
If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately. If they are not available, follow their directions in contacting an emergency facility. Be prepared to provide information about the product and your pet's weight and symptoms.
