Located in the heart of Santa Monica, we are honored to have had the opportunity to renovate one of Main Street’s historic buildings, bringing world-class medicine with hometown care to your neighborhood since 2022. Our entire team is dedicated to creating a positive and stress-free environment for your pets through our Fear Free and Cat Friendly Veterinary Professionals training.
At VCA Santa Monica Main Street Animal Hospital, we pride ourselves on being more than just a veterinary hospital. We are a member of the community dedicated to building lasting relationships with our clients and their animal companions. We partner with VCA Charities and Los Angeles Animal Services to help pets find and remain in loving homes by hosting adoption events and participating in programs such as Dog Day Out. As of January 1, 2026, we have helped 11 dogs find their forever homes.
Located on historic Main Street, we proudly serve Santa Monica, Venice, Mar Vista, and the surrounding areas.
As your local veterinary hospital, we offer primary and preventive care for cats and dogs at every stage of life, from puppies and kittens through adulthood and into their senior years. Our wellness services are designed to support every aspect of your pet’s health. Regular check-ups, vaccinations, and health screenings are essential to a long, healthy life. We work with you to create a customized wellness plan that may include routine services such as annual blood work, fecal testing, spays and neuters, microchipping, allergy and skin relief, and dental care, just to name a few.
We are here to serve you and strive to ensure that every interaction, whether on the phone or in the hospital, leaves you smiling. Ready to schedule your pet’s visit? You can easily book an appointment with us online.
We harness the scale and strength of our global network while acknowledging each individual's contribution. We work locally to improve the lives of all who interact with our brand.
Explore more below.
ASPCA Poison Control Center Hotline
The ASPCA Animal Poison Control Center is staffed 24 hours with veterinary health professionals who have been specially trained in veterinary toxicology. If you think that your pet may have ingested a potentially poisonous substance, call the ASPCA 24 hour emergency Animal Poison Control Center hotline at (888) 426-4435.
Visit ASPCA Poison Control Center
Pet Insurance may help your pet get the best veterinary care when they're sick or injured. There are many providers that offer plans that covers certain unexpected illnesses or injuries throughout your pet's life. Rest assured knowing your pet can receive the best veterinary care, without worrying about the cost.
Our hospital works with Trupanion and can assist you with your pet insurance claim filing needs. We accept Trupanion payment at checkout. To find out more about Trupanion’s insurance coverage and offerings, call 1-855-591-3100 or visit http://trupanion.com/vca.
We accept CareCredit, the pet, health and wellness credit card with flexible, budget-friendly financing options that allow you to pay over time for a range of treatments and services—including procedures, medication and more.*
To learn more about CareCredit, or to see if you prequalify, please visit us.
*Subject to credit approval.
