*Prescription Required: Vetsource®, our pharmacy provider, may need to contact your veterinary hospital for prescription verification. Learn More
Simplicef® is a prescription cephalosporin antibiotic used for the treatment of skin infections such as wounds and abscesses in dogs caused by susceptible strains of bacteria in dogs.
Side effects may include decreased or lack of appetite, nausea/vomiting, or diarrhea.Other side effects may occur, if you notice anything unusual, contact your veterinarian.
Simplicef® is effective against most gram-positive and gram-negative bacteria and is FDA-approved for treating canine bacterial skin infections.
Simplicef® should be given orally as directed by your veterinarian.
Cefpodoxime proxetil is contraindicated in dogs with known allergy to cefpodoxime or to the ?-lactam (penicillins and cephalosporins) group of antibiotics. As with other cephalosporins, cefpodoxime proxetil may occasionally induce a positive direct Coombs’ test. The safety of this medication has not been evaluated in pregnant, breeding, or nursing animals. Use with caution in animals with seizures, epilepsy, or kidney disease.
Make sure to tell your veterinarian what other medication you are giving to your pet. Quite often your veterinarian may prescribe two different medications, even if a drug interaction may occur. In this case, your veterinarian may vary the dose and/or monitor your pet more closely.
Allergic reactions to medications may occur. Be sure to inform VetSource and your veterinarian if your pet has any known drug sensitivities or allergies. If your pet displays symptoms of an allergic reaction, call your veterinarian immediately or go to a veterinary emergency clinic. Symptoms may include but are not limited to: swollen lips, tongue, face, airways; difficulty breathing; agitation; profuse salivation; vomiting; widespread hives and itching.