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Benefits
  • Trifexis kills fleas and prevents flea infestations, prevents heartworm disease, and treats and controls adult hookworm*, roundworm and whipworm infections. *Ancylostoma caninum
How-to

Trifexis® (spinosad + milbemycin oxime) for dogs

Trifexis

*Prescription Required: Vetsource®, our pharmacy provider, may need to contact your veterinary hospital for prescription verification. Learn More

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Product Information

Trifexis is a monthly, beef-flavored chewable tablet for dogs that kills fleas and prevents flea infestations, prevents heartworm disease, and treats and controls adult hookworm*, roundworm and whipworm infections. *Ancylostoma caninum


Trifexis combines two trusted active ingredients to provide protection for dogs against three dangerous types of parasites. Trifexis starts killing fleas in just 30 minutes and killed 100% of fleas in four hours in a controlled laboratory study.


Trifexis comes in a tasty, beef-flavored tablet for easy administration to your dog. Each tablet contains spinosad and milbemycin oxime.

Active Ingredients

Spinosad, milbemycin oxime


Important Safety Information

Serious adverse reactions have been reported following concomitant extra-label use of ivermectin with spinosad alone, one of the components of Trifexis chewable tablets. Treatment with fewer than three monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention. Prior to administration of Trifexis, dogs should be tested for existing heartworm infection. Use with caution in breeding females. The safe use of Trifexis in breeding males has not been evaluated. Use with caution in dogs with pre-existing epilepsy.


The most common adverse reactions reported are vomiting, depression/lethargy, itching, decreased appetite, and diarrhea. To ensure heartworm prevention, observe your dog for one hour after administration. If vomiting occurs within an hour of administration, redose with another full dose. Puppies less than 14 weeks of age may experience a higher rate of vomiting. Like all medications, keep Trifexis out of reach of children. Other side effects may occur. If you notice anything unusual, contact your veterinarian.

Developed For

Dogs

Product Benefits

Trifexis kills fleas and prevents flea infestations, prevents heartworm disease, and treats and controls adult hookworm*, roundworm and whipworm infections. *Ancylostoma caninum

Usage Guidelines

Trifexis should be given orally, as directed by your veterinarian. Give Trifexis with food for maximum effectiveness. View full product label for complete safety information.


Cautions

Treatment with fewer than three monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention. Prior to administration of Trifexis, dogs should be tested for existing heartworm infection. Use with caution in breeding females. The safe use of Trifexis in breeding males has not been evaluated. Use with caution in dogs with pre-existing epilepsy.