Avenanthramide + Ceramide + Chlorhexidine (CeraSoothe)

Lauren R. Forsythe, PharmD, MBA, DICVP; Kayla Hyland, DVM

What is avenanthramide + ceramide + chlorhexidine?

Avenanthramide + ceramide + chlorhexidine (brand name CeraSoothe® CHX) is an antiseptic, antifungal, and skin nourishing agent used in the treatment of surface skin infections and skin reactions in cats and dogs.

The U.S. Food and Drug Administration (FDA) does not review non-drug health products (e.g., herbals, nutraceuticals, shampoos, and other supplements) for safety or effectiveness before they are sold to the public. Manufacturers of non-drug health products must ensure their products are safe and labeled accurately.

The FDA requires that these non-pharmaceuticals contain a disclaimer that says, “This product is not intended to diagnose, treat, cure or prevent any disease.” Health Canada licenses “veterinary health products” after reviewing safety, efficacy, and manufacturing information provided by the manufacturer. These products are not tested by Health Canada.

Your veterinarian is the best source of information about the safety of non-drug health products in pets. Just because a product is natural does not mean it is safe. All medicines and medicinal plants are potentially toxic if used inappropriately or given at high doses. Supplements can also have side effects, like pharmaceuticals. Few supplements and herbs have been subjected to rigorous scientific trials to determine their efficacy.

Although the information in this handout may be helpful, it also may be incomplete and may not represent the full range of effects the supplement could have on your pet.

How do I give my pet avenanthramide + ceramide + chlorhexidine?

  • Avenanthramide + ceramide + chlorhexidine comes in mousse and shampoo forms.
  • All forms are applied topically directly to the skin.
  • Avoid contact with the eyes, nose, and mouth.
  • Follow your veterinarian’s directions for how to use this product.
  • This treatment requires at least 10 minutes of contact time.
  • Give this treatment to your pet for the entire time prescribed by your veterinarian, even if it appears that your pet is feeling better.
 

It can take a few weeks before the full effects of this health product are noted, but gradual improvements are usually noticeable after a few days.

What if I miss giving my pet the treatment?

If you miss an application, give it as soon as you remember and then continue with the regular dosing schedule. However, if it is almost time for the next scheduled application, skip the missed dose and resume the regular schedule. Do not give the pet two doses at once.

Are there any potential side effects?

Avenanthramide + ceramide + chlorhexidine may cause the following side effects:

  • Redness, itching, and/or irritation at site of application
 

Serious adverse reactions may occur. If any of the following signs develop, stop giving avenanthramide + ceramide + chlorhexidine and contact your veterinarian immediately:

  • An allergic reaction such as irregular breathing, rash, fever, puffiness and swelling around the face
 

Sensitivities can develop over time with repeated exposure. Your pet may have no reaction after the first few doses, but may develop a sensitivity later. It is important to watch for signs of an allergic reaction over the entire course of treatment. Other side effects may occur. If you notice anything unusual, contact your veterinarian immediately. This short-acting treatment should stop working within 24 hours.

Are there any risk factors for this treatment?

DO NOT USE avenanthramide + ceramide + chlorhexidine in

  • Pets that are allergic to any of the components.
 

Are there any drug interactions I should be aware of?

There are no documented drug interactions for this medication. Be sure to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your pet is taking before starting any new treatment.

Is any monitoring needed with this treatment?

  • Your veterinarian will let you know when and how they want to reassess your pet to ensure the treatment is working and not causing side effects. In this case, follow your veterinarian’s directions.
  • At home, monitor for any side effects such as those noted above. If any side effects occur, discontinue the treatment, and contact your veterinarian.
 

How do I store avenanthramide + ceramide + chlorhexidine?

  • Store the product in its original container at room temperature.
  • Keep out of reach of children and pets.
 

What should I do in case of emergency?

If you suspect an overdose or an adverse reaction, call your veterinary office immediately. If they are not available, follow their directions in contacting an emergency facility. Be prepared to provide information about the product and your pet’s weight and symptoms. Report any adverse effects to the FDA or Health Canada.

© Copyright 2026 LifeLearn Inc. Used and/or modified with permission under license.

Related Articles