What is carboxymethylcellulose polymer + propylene glycol?
Carboxymethylcellulose polymer + propylene glycol (brand name Intrasite®) is a water-based gel that helps rehydrate wound tissue and helps keep moisture balance to aid in wound healing. It is approved by the U.S. Food and Drug Administration (FDA) as a medical device.
It is used off label (extra label) in veterinary medicine. Many drugs or treatments are commonly prescribed for off-label use in veterinary medicine. “Off label” means the drug or treatment is being used in a way that has not been reviewed or approved by the FDA or Health Canada. In these instances, follow your veterinarian’s directions and cautions carefully, as they may be significantly different from those on the label.
How do I give my pet carboxymethylcellulose polymer + propylene glycol?
- Carboxymethylcellulose polymer + propylene glycol comes in a water-based gel form contained in application packs (Applipak®), available in different sizes.
- Gel is applied topically, directly to the wound.
- Follow your veterinarian’s directions for cleaning the wound before application, bandaging, and wound care.
- Wash your hands before and after applying or wear gloves when applying this medication.
- Avoid contact with eyes.
- Do not let an animal lick or chew the affected sites after application.
- Give this medication to your pet for the entire time prescribed by your veterinarian, even if it appears that your pet is feeling better.
This treatment should take effect soon after application and improvement in clinical signs should follow.
What if I miss applying the product?
If you miss a dose, give it as soon as you remember, and then continue with the regular dosing schedule. However, if it is almost time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not give the pet two doses at once.
Are there any potential side effects?
Carboxymethylcellulose polymer + propylene glycol has no reported side effects, but reactions can occur. If any of the following signs develop, stop using carboxymethylcellulose polymer + propylene glycol and contact your veterinarian immediately:
- An allergic reaction such as irregular breathing, rash, fever, puffiness and swelling around the face
Drug sensitivities can develop over time, with repeated exposure. Your pet may have no reaction after the first few doses but may develop a sensitivity later. It is important to watch for signs of an allergic reaction over the entire course of treatment and notify your veterinarian if you have any concerns. Other side effects may occur. If you notice anything unusual, contact your veterinarian immediately. Carboxymethylcellulose polymer + propylene glycol is easily removed by cleaning with normal saline.
Are there any risk factors for this treatment?
DO NOT USE carboxymethylcellulose polymer + propylene glycol gel in:
- Pets that are allergic to any component
- Pets with severe wounds
Are there any drug interactions I should be aware of?
There are no documented drug interactions for this medication. Be sure to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your pet is taking before starting any new treatment.
Is any monitoring needed with this medication?
- Your veterinarian will let you know when and how they want to reassess your pet to ensure the medication is working and not causing side effects.
- At home, monitor for any side effects such as those noted above. If any occur, stop using the medication and contact your veterinarian.
How do I store carboxymethylcellulose polymer + propylene glycol?
- Store the medication in its original container at room temperature.
- Protect from heat, light, and moisture. Do not freeze.
- Discard medication if the cap is loose.
- Keep medication out of reach of children and pets.
What should I do in case of emergency?
If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately. If they are not available, follow their directions in contacting an emergency facility. Be prepared to provide information about the product and your pet's weight and symptoms.
