What is hydrocortisone aceponate topical?
Hydrocortisone aceponate topical (brand name: Cortavance®) is a topical steroid used to treat inflammatory skin conditions and skin itchiness in dogs. It differs from hydrocortisone as it rapidly penetrates the skin and targets areas of inflammation without significant absorption to the rest of the body.
It may be used off label in cats. Many drugs are commonly prescribed for off-label use in veterinary medicine. “Off label” means the drug is being used in a way that has not been reviewed or approved by the U.S. Food and Drug Administration (FDA) or Health Canada. In these instances, follow your veterinarian’s directions and cautions carefully, as they may be significantly different from those on the label.
This medication is not currently available in the United States.
How do I give my pet hydrocortisone aceponate topical?
- Hydrocortisone aceponate topical is administered topically, with a spray pump.
- To apply, spray about 10 cm (4 inches) away from the skin.
- Two pumps delivers enough medication to cover a 10 x 10 cm (4 x 4 inch) square area.
- Leave treated area to dry. Prevent your pet from licking or chewing the area until dry.
- Spray in a well-ventilated area.
- Follow the specific directions your veterinarian provides.
- Do not spray more than a third of the body.
- Use gloves or wash your hands after applying products with hydrocortisone aceponate.
- Avoid contact with your pet’s eyes or any ulcerated skin.
- Give this medication to your pet for the entire time prescribed by your veterinarian, even if it appears that your pet is feeling better.
This medication should begin working within 1 to 2 hours of administration.
What if I miss giving my pet the medication?
If you miss a dose, give it as soon as you remember, and then continue with the regular dosing schedule. However, if it is almost time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not give the pet two doses at once.
Are there any potential side effects?
Hydrocortisone aceponate topical may cause the following side effects:
- A skin reaction at the site of application: redness, itching
- Reversible hormone suppression in cases of chronic overdose
Drug sensitivities can develop over time, with repeated exposure. Your pet may have no reaction after the first few doses but may develop a sensitivity later. It is important to watch for signs of an allergic reaction over the entire course of treatment and notify your veterinarian if you have any concerns.
Other side effects may occur. If you notice anything unusual, contact your veterinarian immediately. This short-acting medication should stop working within a few days, although effects can be longer in pets with liver or kidney disease.
Are there any risk factors for this medication?
DO NOT USE hydrocortisone aceponate topical in:
- Pets that are allergic to any component
- Pets under 7 months old
- Pets with hypoadrenocorticism (Cushing’s disease)
- Pets with ulcerative skin lesions
- Pets with skin tuberculosis
- Pets that are sick or debilitated
- Pets that are pregnant, may become pregnant, or are nursing, as safety has not been established
Are there any drug interactions I should be aware of?
Hydrocortisone aceponate topical should NOT BE USED within two weeks of skin or blood allergy testing.
Hydrocortisone aceponate topical should be USED WITH CAUTION with:
- Other corticosteroids (e.g., dexamethasone, prednisone, prednisolone)
- Other topical medications used to treat the same lesion
Be sure to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your pet is taking before starting any new treatment.
Is any monitoring needed with this medication?
- No specific monitoring is required while your pet is taking this medication.
- Your veterinarian may monitor your pet to be sure that the medication is working.
- At home, monitor for any side effects such as those noted above. If any occur, stop using the medication and contact your veterinarian.
How do I store hydrocortisone aceponate topical?
- Store in the supplied container below 77°F (25°C). Do not allow it to freeze.
- Keep container closed when not in use to protect the medication from light and humidity.
- Discard medication 6 months after opening.
- Keep the container out of reach of children and pets.
What should I do in case of emergency?
If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately. If they are not available, follow their directions in contacting an emergency facility. Be prepared to provide information about the product and your pet's weight and symptoms.
