What is nystatin, neomycin sulfate, thiostrepton, and triamcinolone topical/otic?
Nystatin, neomycin sulfate, thiostrepton, and triamcinolone topical/otic (brand names Animax®, Dermalog®, Panalog®, Quadritop®) is a combination antimicrobial (neomycin, thiostrepton), antifungal (nystatin), and steroid (triamcinolone) medication used to treat infections and inflammation of the skin, ears, and anal glands in cats and dogs.
It may be used “off label” or “extra label” in other animals and for other conditions. Many drugs are commonly prescribed for off-label use in veterinary medicine. In these instances, follow your veterinarian’s directions and cautions carefully.
How do I give my pet nystatin, neomycin sulfate, thiostrepton, and triamcinolone topical/otic?
Nystatin, neomycin sulfate, thiostrepton, and triamcinolone topical/otic comes in an ointment form.
- Ointments are given topically, directly onto the affected area.
- Avoid contact with eyes, mouth, and nose.
- Trimming of fur surrounding the affected area may be recommended.
- Do not allow the dropper tip to touch your animal’s skin or any other surface to prevent contamination.
- Do not allow contact with the application site for at least 20 minutes after applying the medication.
- Give this medication to your pet for the entire time prescribed by your veterinarian, even if it appears that your pet is feeling better.
What if I miss giving my pet the medication?
If you miss a dose, give it as soon as you remember, and then continue with the regular dosing schedule. However, if it is almost time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not give the pet two doses at once.
Are there any potential side effects from nystatin, neomycin sulfate, thiostrepton, and triamcinolone topical/otic?
Nystatin, neomycin sulfate, thiostrepton, and triamcinolone topical/otic may cause the following side effects:
- irritation, itching or reddening at site of application
The following reactions are rare; if they occur, contact your veterinarian immediately:
- an allergic reaction such as irregular breathing, rash, fever, puffiness and swelling around the face
- sudden hearing loss, head tilt, and/or walking in circles
Drug sensitivities can develop over time with repeated exposure. Your pet may have no reaction after the first few doses, but may develop a sensitivity later. It is important to watch for signs of an allergic reaction over the entire course of treatment.
Other side effects may occur. If you notice anything unusual, contact your veterinarian immediately. This moderate-acting medication should stop working within a few days.
Are there any risk factors for this medication?
This medication should NOT BE USED in animals that:
- are allergic to any component
- have a ruptured ear drum
- have a suspected tuberculosis skin infection
This medication should be USED WITH CAUTION in animals that:
- have a small body size (e.g., toy breeds)
- have recurring ear infections
- require treatment on a large area
Are there any drug interactions I should be aware of?
No known drug interactions have been reported for this medication. Be sure to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your pet is taking before starting any new treatment.
Is any monitoring needed with this medication?
Your veterinarian may schedule a follow-up visit for after the course of medication is complete to ensure the infection has been cleared and/or do additional testing to ensure this is the right medication for the type of infection that is present. In this case, follow your veterinarian’s directions.
How do I store nystatin, neomycin sulfate, thiostrepton and triamcinolone topical/otic?
- Store the medication in its original container at room temperature, protected from light.
- Follow storage and expiration recommendations for specially compounded formulas.
- Keep medication out of reach of children and pets.
What should I do in case of emergency?
If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately. If they are not available, follow their directions in contacting an emergency facility.
